GLP-1 medications reduce appetite, which is the point. But eating less food can also mean getting fewer vitamins, minerals and fiber. Here's what nutrition experts recommend, and where simple supplements fit in.
Written by Vita Globe Editorial Team | Reviewed against peer-reviewed research and NIH guidance | Updated October 26, 2026
What supplements should you take on a GLP-1?
A 2025 joint advisory from four major nutrition and obesity medicine organizations notes that reduced food intake on GLP-1 therapy can raise the risk of nutrient shortfalls, and it emphasizes adequate protein, fiber, fluids and micronutrients[1]. A daily multivitamin can help cover gaps[2], fiber supports regularity, and magnesium is a nutrient many adults already fall short on[3]. Supplements support nutrition. They don't change how the medication works, and food and protein come first.
Sources: Joint Advisory 2025 · NIH Multivitamin Fact Sheet · NIH Magnesium Fact Sheet · Verified 2026-10-26
IN THIS ARTICLE
Why nutrition gets harder on a GLP-1
GLP-1 medications slow stomach emptying and reduce hunger, so many people eat noticeably smaller meals. That helps with weight goals, but smaller portions also mean less room for vitamins, minerals, protein and fiber. Common side effects like nausea can make it even harder to eat a varied diet[1]. New to the topic? Start with What Is GLP-1? The Hormone Behind the Headlines.
What the experts recommend
In 2025, the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association and The Obesity Society published joint nutrition priorities for people on GLP-1 therapy[1]. Key themes include:
- Prioritizing protein to help preserve muscle while losing weight
- Getting enough fiber and fluids to support digestion and regularity
- Watching for micronutrient shortfalls, since eating less can mean getting less of key vitamins and minerals
- Strength training and working with a care team
Where a multivitamin, fiber and magnesium fit
- Multivitamin: a simple nutrition safety net when you're eating less overall. Multivitamins are designed to help fill common gaps, not replace food[2].
- Fiber: most adults already fall short of fiber recommendations[4], and smaller meals can widen that gap. A sugar-free prebiotic fiber gummy is an easy add-on to fiber-rich foods.
- Magnesium: involved in muscle and nerve function and energy production, and many adults get less than recommended from food[3].
The honest summary
- Food and protein come first. Supplements fill gaps around them.
- A multivitamin, fiber and magnesium are basics, not GLP-1 boosters.
- Your doctor or dietitian can check for specific deficiencies with bloodwork.
What supplements can't do
No supplement replaces, mimics or enhances a GLP-1 medication, and you should be skeptical of any product that claims to. These are everyday nutrition supplements for people eating less, whatever the reason. Also on the topic: Hair Loss on GLP-1s: What's Actually Happening.
Our option
The GLP-1 Nutrition Companion
Our vegan Adult Multivitamin Gummies, Sugar-Free Prebiotic Fiber Gummies (2.7g) and Magnesium Citrate Gummies (70mg) in one bundle. Three 60ct bottles, third-party tested. A nutrition routine, not a weight-loss product.
Frequently asked questions
Can I take vitamins while on a GLP-1 medication?
Most people can, but check with your doctor or pharmacist first, especially if you take other prescriptions. GLP-1 medications slow digestion, which can affect how some oral medications are absorbed.
Does fiber help with GLP-1 side effects?
Fiber and fluids support regularity, which is why experts emphasize both[1]. If you have ongoing constipation, nausea or stomach pain, talk to your prescriber.
Do I still need protein?
Yes. Protein is a top priority on GLP-1 therapy to help maintain muscle[1], and this bundle doesn't provide it. Build meals around protein foods first.
Sources
- Nutritional priorities to support GLP-1 therapy for obesity: A joint Advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society. 2025. pmc.ncbi.nlm.nih.gov/articles/PMC12304835
- National Institutes of Health, Office of Dietary Supplements. Multivitamin/mineral Supplements — Fact Sheet for Health Professionals. ods.od.nih.gov/factsheets/MVMS-HealthProfessional
- National Institutes of Health, Office of Dietary Supplements. Magnesium — Fact Sheet for Health Professionals. ods.od.nih.gov/factsheets/Magnesium-HealthProfessional
- U.S. Department of Agriculture and U.S. Department of Health and Human Services. Dietary Guidelines for Americans, 2020-2025. dietaryguidelines.gov
About the Vita Globe Editorial Team
The Vita Globe Editorial Team researches and writes our wellness content, working from peer-reviewed research, systematic reviews and guidance from bodies such as the NIH and the FDA. We cite our sources inline and update articles when the evidence changes.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This article is for informational purposes only and is not a substitute for medical advice. Talk to your healthcare provider before starting any new supplement, particularly if you are pregnant, nursing or taking prescription medication, including GLP-1 medications.
