Moodiness, irritability and tension before your period are common, and a few nutrients and botanicals come up again and again in the research. Here's what's in the Her Cycle Duo and what each piece does.
Written by Vita Globe Editorial Team | Reviewed against peer-reviewed research and NIH guidance | Updated October 26, 2026
Do B6, chasteberry and magnesium help with PMS?
Vitamin B6 and chasteberry are two of the most studied supplements for PMS symptoms. Some studies suggest chasteberry may ease symptoms like irritability and breast tenderness, though study quality varies[1], and B6 has been studied for premenstrual mood symptoms with mixed results[2]. Magnesium contributes to normal muscle and nerve function, and many women get less than recommended from food[3].
Sources: NCCIH Chasteberry · NIH Vitamin B6 · NIH Magnesium · Verified 2026-10-26
IN THIS ARTICLE
What's inside
- Her PMS Gummies, 60ct: 20mg vitamin B6 plus a 111mg blend of chasteberry (vitex), cranberry and dong quai per two-gummy serving. Vegan strawberry gummy.
- Magnesium Citrate Gummies 70mg, Vegan, 60ct
What the research says
Chasteberry (Vitex agnus-castus) has been used for women's health for centuries. According to the NIH's National Center for Complementary and Integrative Health, some research suggests it may help with PMS symptoms, but many studies were small or not well designed[1].
Vitamin B6 helps your body make neurotransmitters, including serotonin. It has been studied for premenstrual symptoms, with some trials showing improvement in mood-related symptoms and others showing little effect[2].
Magnesium is involved in muscle and nerve function, and national surveys show many people fall short[3]. It's a popular, gentle addition to a cycle-support routine.
The honest summary
- B6 and chasteberry have the most research for PMS among supplements, but evidence is still mixed.
- Most studies used daily use for two to three cycles, so be patient.
- Severe symptoms deserve a conversation with your doctor, not just supplements.
More in Her B6 Gummies: Vitamin B6 for Women, Explained.
Our option
The Her Cycle Duo
Her PMS Gummies plus Magnesium Citrate Gummies. Two 60ct bottles, both vegan and third-party tested, for less than buying them separately.
Who should check with a doctor first
Chasteberry may affect hormone-related medications, including birth control and hormone therapy, and dong quai may interact with blood thinners[1]. Don't take this bundle if you're pregnant, nursing, trying to conceive or under 18, and talk to your doctor if you have a hormone-sensitive condition or take any prescription.
Frequently asked questions
When should I take it?
Follow each label. Most people take it daily throughout the month, since research looked at consistent daily use.
How long until I notice a difference?
Give it about three cycles of consistent use before deciding.
Is it vegan?
Yes, both gummies are vegan.
Sources
- National Center for Complementary and Integrative Health. Chasteberry. nccih.nih.gov/health/chasteberry
- National Institutes of Health, Office of Dietary Supplements. Vitamin B6 — Fact Sheet for Health Professionals. ods.od.nih.gov/factsheets/VitaminB6-HealthProfessional
- National Institutes of Health, Office of Dietary Supplements. Magnesium — Fact Sheet for Health Professionals. ods.od.nih.gov/factsheets/Magnesium-HealthProfessional
About the Vita Globe Editorial Team
The Vita Globe Editorial Team researches and writes our wellness content, working from peer-reviewed research, systematic reviews and guidance from bodies such as the NIH and the FDA. We cite our sources inline and update articles when the evidence changes.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This article is for informational purposes only and is not a substitute for medical advice. Talk to your healthcare provider before starting any new supplement, particularly if you are pregnant, nursing or taking medication.
