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ACV Gummies Side Effects: What to Know Before You Start

Apple cider vinegar gummies are generally mild, and they avoid the biggest problem with liquid vinegar: acid on your teeth and throat. But "natural" doesn't mean side-effect-free. Here's what's been reported, and what's specific to the gummy format.

Written by Vita Globe Editorial Team | Reviewed against systematic reviews, case reports and professional guidance

What are the side effects of ACV gummies?

For most healthy adults taking the labeled amount, side effects are uncommon and mild, such as stomach upset or nausea. Vinegar's more serious reported problems, including throat injury, tooth erosion and low potassium, involved undiluted liquid, tablets or very large amounts over time[1][2][3]. Gummies add their own considerations: sugar, or sugar alcohols in sugar-free versions[4].

Caveat: There are no formal safety studies of ACV gummies, and long-term safety data on apple vinegar in general are limited[1].

Sources: Launholt 2020 · Hill 2005 · Lhotta 1998 · Lenhart 2017 · Verified 2026-09-27

Can ACV gummies upset your stomach?

Some people notice mild digestive effects when they start. With liquid vinegar, nausea is a documented effect: in one study, vinegar drinks reduced appetite largely because they made participants feel nauseated[5]. Gummies deliver far less vinegar, so this is less likely, but if you feel queasy, try taking your gummy with food.

Vinegar can also slow how quickly the stomach empties. In a pilot study of people with type 1 diabetes and gastroparesis, apple cider vinegar with a meal slowed emptying further[6]. For most people that's not a concern, but if you already have delayed stomach emptying, it matters.

Are ACV gummies bad for your teeth or throat?

This is where gummies have a real advantage over liquid. A systematic review of apple vinegar safety noted reports of tooth erosion and throat or esophageal injury, mostly linked to undiluted vinegar or vinegar tablets[1].

One well-known report described esophageal injury after an apple cider vinegar tablet became lodged in the throat. The researchers then tested eight ACV tablet products and found that acetic acid content varied widely and labels were often inaccurate[2]. A chewable gummy isn't the same as a hard tablet or a straight shot of vinegar, but chewing thoroughly and following the label is still sensible. Like any sweet chewable, brushing your teeth as part of your normal routine is a good idea.

Can apple cider vinegar lower potassium?

In very large amounts over time, possibly. A published case described a 28-year-old woman who consumed about 250 mL of cider vinegar a day for six years and developed very low potassium, high renin levels and bone density in the osteoporotic range[3].

That's roughly a cup of vinegar every day for years, which is nothing like a gummy serving. But it's the reason people who take medications that affect potassium, such as certain diuretics, or who have kidney disease, should talk to their doctor before using vinegar products regularly.

What about the sugar and sweeteners in gummies?

This is the side of ACV gummies that often gets overlooked.

  • Regular gummies contain sugar. The American Heart Association recommends limiting added sugars, suggesting no more than about 100 calories a day for most women and 150 for most men[7]. A gummy or two is a small amount, but it counts, especially if you take several gummy supplements.
  • Sugar-free gummies often use sugar alcohols (polyols). A systematic review found that polyols can cause gas, bloating and loose stools, especially in larger amounts and in people with IBS[4]. Check the label to see which sweetener your gummy uses.
  • Added vitamins. Some ACV gummies include B vitamins, folate or iodine, which can add up if you also take a multivitamin.

More on this in Sugar-Free vs. Regular ACV Gummies and what "sugar-free" actually means on gummy vitamins.

Who should talk to a doctor first?

  • People taking insulin or other blood sugar medication, since vinegar may lower post-meal blood sugar
  • People with gastroparesis or other digestive conditions[6]
  • People taking diuretics or other medications that affect potassium, or with kidney disease[3]
  • People with IBS who are sensitive to sugar alcohols[4]
  • Anyone pregnant or breastfeeding

The honest summary

  • At labeled amounts, ACV gummies are unlikely to cause more than mild stomach upset in healthy adults.
  • Serious vinegar problems in the literature involved undiluted liquid, tablets or very large amounts over years.
  • Gummies bring their own trade-offs: sugar in regular versions, possible gas or bloating from sugar alcohols in sugar-free ones.
  • Check with your doctor if you take blood sugar or potassium-affecting medications.

Our option

Vita Globe Apple Cider Vinegar Gummies 500mg, 60ct

A simple serving that's easy to stick to: one gummy a day, preferably with a meal, with 500mg of apple cider vinegar with "The Mother." Vegan, non-GMO and gluten-free, with no sour bite on your teeth. Every Vita Globe product is tested by an independent third-party lab.

Shop ACV Gummies 60ct

Frequently asked questions

Can ACV gummies cause diarrhea?

It's possible, especially with sugar-free gummies that contain sugar alcohols, which can cause loose stools in larger amounts[4]. Stick to the labeled serving.

Do ACV gummies make you poop?

There's no evidence that apple cider vinegar itself acts as a laxative. If you notice changes, sweeteners are a more likely cause.

Can ACV gummies cause acid reflux?

We didn't find good studies on this. Some people with reflux find acidic foods bother them, so if you notice heartburn, stop and talk to your doctor.

Are ACV gummies bad for your kidneys?

At labeled amounts in healthy adults, there's no evidence of harm. Very large vinegar intake over years has been linked to low potassium[3], so people with kidney disease should ask their doctor first.

Can I take ACV gummies with medication?

Ask your doctor or pharmacist, especially about insulin, diabetes medications, diuretics and heart medications that interact with potassium levels.

Sources

  1. Launholt TL, Kristiansen CB, Hjorth P. Safety and side effects of apple vinegar intake and its effect on metabolic parameters and body weight: a systematic review. Eur J Nutr. 2020;59(6):2273-2289. doi:10.1007/s00394-020-02214-3
  2. Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc. 2005;105(7):1141-1144. doi:10.1016/j.jada.2005.04.003
  3. Lhotta K, Höfle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron. 1998;80(2):242-243. doi:10.1159/000045180
  4. Lenhart A, Chey WD. A systematic review of the effects of polyols on gastrointestinal health and irritable bowel syndrome. Adv Nutr. 2017;8(4):587-596. doi:10.3945/an.117.015560
  5. Darzi J, Frost GS, Montaser R, Yap J, Robertson MD. Influence of the tolerability of vinegar as an oral source of short-chain fatty acids on appetite control and food intake. Int J Obes. 2014;38(5):675-681. doi:10.1038/ijo.2013.157
  6. Hlebowicz J, Darwiche G, Björgell O, Almér LO. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. BMC Gastroenterol. 2007;7:46. doi:10.1186/1471-230X-7-46
  7. Johnson RK, Appel LJ, Brands M, et al. Dietary sugars intake and cardiovascular health: a scientific statement from the American Heart Association. Circulation. 2009;120(11):1011-1020. doi:10.1161/CIRCULATIONAHA.109.192627

About the Vita Globe Editorial Team

The Vita Globe Editorial Team researches and writes our wellness content, working from peer-reviewed research, systematic reviews and guidance from bodies such as the NIH and the FDA. We cite our sources inline and update articles when the evidence changes.

Read our editorial standards →

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. This article is for informational purposes only and is not a substitute for medical advice. Talk to your healthcare provider before starting any new supplement, particularly if you are pregnant, nursing, taking medication, or caring for a child.

Disclaimer: The information and content on this website is provided only for informational purposes. It is not meant in any way as a substitute for the professional advice provided by your physician or any other healthcare professional. The statements on this site have not been evaluated by the FDA. Our products are not intended to diagnose, treat, cure or prevent any disease.

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